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The potential health benefits of mushrooms have captured the attention of both researchers and users. Magic mushrooms, renowned in indigenous cultures for their mystical and therapeutic properties, have become a focal point of rigorous scientific inquiry. This newfound interest stems from their alleged capacity to impact mental health, cognition, and overall well-being positively. 

Let us delve into the captivating world of magic mushrooms and their potential to benefit human health. 

Health benefits of mushrooms

What is Magic Mushroom and What Does it Contain?

Magic mushrooms house the psychoactive compounds psilocybin and psilocin, which are accountable for inducing hallucinogenic effects. Magic mushrooms, recognized by their unique cap and stem, originate from diverse species worldwide.

Psilocybin, the primary psychoactive compound, transforms into psilocin in the body, engaging serotonin receptors in the brain. This interaction leads to altered perceptions, mood changes, and profound mystical or introspective experiences. 

Psilocybin: The Life-Changing Shroom Compound

Psilocybin is a naturally occurring psychoactive compound. When ingested, psilocybin turns to psilocin, another psychoactive compound. This psychoactive compound will produce hallucinations and other shroom experiences.

What makes psilocybin particularly intriguing is its potential to address various conditions. According to Matthew W. Johnson, Ph.D., its most promising application is treating addiction. 

In an ongoing study on nicotine addiction, Dr. Johnson’s research also showed impressive outcomes: 80% of those who received psilocybin therapy quit smoking, and 60% remained smoke-free 16 months later. This success rate is significantly higher than varenicline, the most effective among other smoking cessation methods. Dr. Johnson stresses that psilocybin has the potential to tackle both withdrawal symptoms and the psychological aspects of addiction.

Understanding the Benefits of Shrooms

People have long associated magic mushrooms with their hallucinogenic effects. This has fascinated and intrigued countless individuals. Their potential goes far beyond the psychedelic experience, offering a diverse array of health benefits that are gradually gaining recognition. 


In a 2022 study published in Sage Journals, scientists investigated the impact of psilocybin on 27 individuals who had struggled with depression. Over a span from August 2017 to April 2019, participants received two doses of psilocybin every two weeks.

The study showed that participants maintained consistently low depression levels at 1, 3, 6, and 12 months after treatment.


Many patients experience various anxiety disorders, with a significant portion showing symptoms of Generalized Anxiety Disorder (GAD). Psilocybin influences the brain’s serotonin receptors, primarily targeting the 5-HT receptors. This action serves to elevate mood and alleviate excessive anxiety-like states. 

The psychedelic qualities of this substance elicit feelings of well-being and euphoria in individuals undergoing treatment. Regions such as the Limbic System are frequently affected by psilocybin and related compounds found in magic mushrooms.

This compound operates within the Hippocampus and Thalamus, consequently diminishing the levels of the stress hormone Cortisol. It mitigates the surge of adrenaline that commonly ensues in individuals suffering from GAD.

Substance Abuse Therapy

Conditions like smoking and alcohol abuse can lead to severe systemic illnesses affecting the respiratory and hepatic systems. Individuals with chronic drug dependencies must slow down or abstain from substance use. This is where psilocybin therapy becomes valuable. Enriched with potent compounds, it significantly alleviates withdrawal symptoms.

Psilocybin therapy operates by instilling a sense of responsibility and enhancing cognitive faculties in drug abusers. This improvement enables them to make more informed judgments and distinguish between right and wrong.

Prolonged psilocybin therapy has demonstrated its efficacy in reducing Substance Abuse Disorders. The compound modifies the patient’s thought processes, reasoning abilities, and logical thinking.

Obsessive-Compulsive Disorder

Obsessive-Compulsive Disorder (OCD) ranks among the most prevalent psychiatric conditions afflicting individuals worldwide. Patients contend with recurring thoughts and perform repetitive rituals to counteract these perceptions. Common compulsions include actions like handwashing, door-closing, and clapping. No prescription medication has provided a complete cure for individuals with OCD.

Research indicates that psilocybin therapy can instill a sense of contentment and reshape thought perception. It finds extensive use in alleviating symptoms in OCD patients. Instead of cognitive behavioural therapy, psychiatrists increasingly use psilocybin therapy once or twice to alleviate these symptoms. This approach notably reduces adverse side effects like nausea, dizziness, and headaches.

Psilocybin modulates the serotonin receptors (5-HT) and augments serotonin production. As serotonin levels gradually increase, patients experience a heightened sense of tranquillity and happiness.


Reports suggest that a substantial dose of psilocybin mushrooms can positively influence an individual’s character. Those who have experienced psilocybin have reported a sustained sense of openness in their personalities that endured for up to a year.

This newfound openness represents a psychological shift characterized by an enhanced appreciation for new experiences. This “open” personality trait can lead to profound insights and foster a keen interest in the world. 


Mushrooms offer a fascinating array of potential health benefits that have garnered the attention of both researchers and users. Magic mushrooms have transcended their traditional use to become subjects of rigorous scientific investigation.

They can address addiction and alleviate symptoms of depression and anxiety or reshape personality traits. As we continue to uncover the myriad ways in which mushrooms can positively impact our health, it is an exciting journey filled with promise. Responsible exploration, coupled with ongoing scientific research, holds the potential to unlock even more of the health benefits.

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Frequently Asked Questions

How can I Incorporate shrooms into my daily routine?

To safely integrate magic mushrooms into your daily routine, approach them thoughtfully and responsibly. Avoiding high doses of psilocybin daily is advisable due to the risk of developing a tolerance to the substance. A more effective method for daily use is microdosing. 

Microdosing involves consuming small, controlled amounts of psilocybin on a regular schedule. This approach allows you to experience the potential benefits of psilocybin without the accompanying hallucinations or overwhelming effects.

How many mushrooms should I ingest to enjoy the benefits?

The number of mushrooms you should ingest to experience the benefits of psilocybin can vary significantly based on several factors. To simplify, there are two ways to experience the benefits of shrooms.

DosageEffectsWhen to Use
Macrodosing1.5 grams and aboveFor a full psychedelic experience, where you intend to have hallucinatory effects and introspective journeys.Occasionally
Microdosing0.1 to 1 gramThe idea is to consume a dose so low that you don’t experience significant psychedelic effects but may still notice subtle improvements in mood, focus, or creativity.Scheduled basis

Are there potential risks associated with using psilocybin?

Individuals with a history of conditions like schizophrenia should avoid psilocybin due to its potential to worsen or trigger underlying psychosis. Chronic use of psilocybin also carries cardiovascular risks as it binds to HT2B receptors, which can lead to adverse changes in the heart valves. Although experts believe this risk is less significant when using the drug infrequently for therapeutic purposes, it’s important to exercise caution.

Can you build tolerance with shrooms?

Yes, tolerance can develop with the use of magic mushrooms. When someone takes magic mushrooms, their body can build up a tolerance to the effects. To overcome this tolerance, individuals must wait several days or weeks before retaking magic mushrooms.

How to use shrooms safely?

If you’re contemplating trying magic mushrooms, use them safely to minimize potential adverse experiences or complications. 

  1. Begin with a low dose: Starting with a low dose is essential to assess tolerance and individual response to magic mushrooms.
  2. Choose a secure and comfortable setting: Opt for a safe environment free from distractions and potential hazards.
  3. Avoid combining with other substances: Refrain from mixing magic mushrooms with other substances, including alcohol and other drugs.
  4. Enlist a trusted companion: It’s wise to have a reliable friend present when using magic mushrooms.

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