Malabar Cubensis is making headlines for its potential to manage chronic pain. While psilocybin mushrooms are associated with mental health breakthroughs, recent findings reveal their effectiveness in easing physical discomfort, too.
One condition gaining attention is Complex Regional Pain Syndrome, a rare and severe disorder known for being incredibly hard to treat. This discovery opens new doors for those living with relentless aches.
Table of Contents
Key Takeaways:
- Psychedelic mushrooms, like Malabar Cubensis, alter ache perception and enhance emotional well-being by interacting with serotonin pathways.
- A refractory CRPS case demonstrated long-term symptom relief, including significant pain reduction and mood improvement, following guided psilocybin therapy.
- Psilocybin may help patients by reducing inflammation, rewiring neural pathways (neuroplasticity), and calming overactive signals.
What Is Complex Regional Pain Syndrome?
This is a long-lasting and painful neuropathic condition, causing intense, persistent pain that doesn’t match the original injury. It can develop after trauma or even occur on its own. Various factors, including sympathetic and central nervous system issues and genetic, inflammatory, and psychological influences, cause the condition.
CRPS can greatly affect the quality of life, causing sensory, motor, and autonomic symptoms that are tough to treat. Standard treatments like physical therapy, medications, and procedures often don’t work, especially in stubborn cases. This has led to growing interest in alternative therapies, such as psychedelics.
Recent studies suggest that Malabar Cubensis, a strain known for its psychoactive properties, may offer hope for managing this condition. These magic shrooms contain compounds that interact with the brain’s pathways to alter ache perception and improve emotional health.
Malabar Cubensis for Chronic Pain Therapies
Malabar magic mushroom, also called Malabar India or MLBR, is a well-known variant of the Psilocybe cubensis mushroom.
| Characteristic | Description |
| Habitat | Found in bovine and equine dung, as well as enriched soils. |
| Climate | Thrives in subtropical regions. |
| Strain Origin | Native to the Malabar Coast, India. |
| Cap | Broadly convex to flat (50+ mm). Yellowish-brown, maturing to yellow with a darker center. Dry surface with veil spots. White flesh bruises bluish-green. |
| Stem | 150 mm long, yellowish. Flesh bruises bluish-green when injured. Features a persistent ring that may remain even when mature. |
| Gills | Grayish when young, darkening with maturity. |
| Spores | Dark purplish-brown, subellipsoid, found on 4-spored basidia. Poor spore depositor, specimens available for microscopy in spore syringe form. |
| Psilocybin Content | 0.81% and total tryptamine content of 0.87%. |
Malabar coast mushrooms produce both physical and psychological effects. Many users report feelings of deep connection with nature, stress relief, and creative breakthroughs.
- Physical Effects: Changes in heart rate, mild nausea, or muscle relaxation.
- Psychological Effects: Intense visual enhancements, brighter colours, and intricate patterns.
Refractory CRPS Pain Treated with Psilocybin – A Case Report
A 54-year-old woman with refractory CRPS experienced significant symptom relief with the hallucinogenic compound, marking the second reported case of its kind.
Methods
The patient, diagnosed with CRPS in 2010, had a history of unsuccessful treatments, including antidepressants, antiepileptics, ketamine, and spinal cord stimulation. Over time, her discomfort persisted at 9/10 severity, accompanied by symptoms such as allodynia, skin discoloration, and falls.
In 2023, the patient discontinued ketamine therapy and initiated guided psychedelic treatment using Psilocybe cubensis mushrooms (2g, 5.5g, and 3.5g over five days). These sessions were combined with neuromechanics, neurovisual modulation, and tactile reprocessing, which she had previously attempted without significant benefit.
Results
Following the treatment, the patient reported dramatic improvements:
- Pain Reduction: This was decreased to 0–1/10, sustained for nine months without ketamine.
- Glossodynia Relief: Attack frequency, intensity, and duration reduced by 75%, with maximum intensity capped at 2/10.
- Fall Frequency: Falls decreased by 75%, with only two falls in nine months.
- Mood Improvement: Significant reductions in depression and PTSD symptoms were recorded using standardized scales.
No adverse reactions were observed.
Discussion
This case shows that psilocybin could be a promising new therapy for long-term symptom relief when traditional treatments didn’t work. Its ability to ease pain may come from its effects on serotonin, particularly its action on the 5-HT2A receptor.
Unlike previous cases using microdoses, this one involved higher doses, which provided longer-lasting relief with fewer treatments. However, more research is needed on side effects, dosing strategies, and how people respond differently.
Although promising, psilocybin is still classified as a Schedule I drug, so more controlled studies are needed. Combining psychedelics with other treatments could improve results by addressing the complicated nature of the condition.
How Psilocybin Works for Pain Management
This active compound in hallucinogenic mushrooms works by influencing the brain’s serotonin system. Serotonin is a key neurotransmitter that affects mood, perception, and discomfort. It binds to serotonin receptors (the 5-HT2A receptor), altering ache perception. By activating this receptor, the compound changes how the brain processes these signals, making it feel less intense or distressing.
Anti-Inflammatory Effects
Chronic discomfort accompanies inflammation. This treatment has shown the potential to reduce inflammation in the body, helping to calm those overactive signals. It can provide relief for conditions where inflammation makes symptoms worse.
Boosting Neuroplasticity
Neuroplasticity is the brain’s ability to form new connections and adapt to changes. The compound promotes neuroplasticity, helping the nervous system “rewire” itself. For people with chronic illness, the compound may help the brain find healthier ways to manage discomfort, break persistent discomfort cycles, and recover from nerve damage.
Safe Use of Psilocybin for CRPS
Using magic mushrooms to manage this condition should always be done under the supervision of a healthcare professional who is knowledgeable about these psychedelic substances. Psychedelics can have strong results, and self-dosing can be dangerous, especially for those with medical conditions.
A specialist can provide a safe setting, monitor the session, and offer guidance throughout the experience. This can help mitigate risks and monitor any adverse reactions that may occur.
Understanding the dosage is important for its effectiveness and safety. Dosages can vary widely based on age, weight, and the severity of symptoms.
Follow several safety measures:
- Start with a low dose of 1 to 2 grams of dried mushrooms to see how your body reacts.
- Gradually increase the dose under professional guidance based on your response if needed.
- Don’t increase the dose without medical supervision—higher doses don’t always mean better results.
- Choose a safe, calm, and familiar place to relax and feel comfortable.
- Always have a sober, trusted person who understands the effects to help if negative reactions occur.
- Prepare mentally and emotionally by discussing the experience with a therapist if necessary and securing your stable state of mind.
- Avoid mixing shrooms with alcohol, other drugs, or medications unless you have professional advice, as it can cause unpredictable reactions and increase risks.
- After the session, stay in a safe space, ideally with someone you trust, to monitor and recover from any lingering effects.
Final Thoughts
Psilocybin shows promise as a treatment for refractory CRPS, and more clinical trials are needed to fine-tune dosing and evaluate long-term effectiveness. It’s important to use magic mushrooms from shrooms delivery online services under the supervision of a healthcare professional experienced with these substances. Make sure you’re in a safe environment and have proper guidance during the experience.
Frequently Asked Questions
How To Consume Malabar Magic Mushrooms for Easing Refractory CRPS Pain?
- Raw or Dried: Eaten as-is for a quick onset of effects, typically within 20–40 minutes.
- Brewed as Tea: This method provides a smoother experience, with effects beginning within 20–40 minutes and peaking after 2–3 hours. The overall experience lasts 4–7 hours.
- Capsules: Ground shrooms in capsules allow for gradual effects, with onset, peak, and duration similar to tea.
These consumption methods affect how quickly the effects start and how intense and long-lasting the experience is.
How Does Cultivating Malabar Coast Mushrooms Differ From Other Psychedelic Shrooms?
The cultivation involves a meticulous process:
- Inoculation: Using nutrient-rich substrates like brown rice flour or grain spawn with spores.
- Ideal Conditions: Maintaining optimal temperature, fresh air exchange, and indirect light.
- Fruiting Bodies: Under these conditions, cubensis strains form fruiting bodies that yield potent results, especially in the first flush. These conditions are crucial for fruiting bodies to grow.
Additionally, the process can vary with different types of mushrooms. For example, agaricus bisporus, one of the most widely cultivated mushrooms, has specific needs. The right fruiting conditions for each type are necessary for a successful harvest.
Can CRPS Lead to Other Health Complications?
Yes, this involves complex nervous, immune, and psychological interactions. If left untreated or poorly managed, it can lead to issues like muscle atrophy, joint stiffness, depression, anxiety, and a lower quality of life.
